Details
Quality Factory Sells Top Purity 99% 1-Aminocyclopropanecarboxylic acid 22059-21-8 with Safe Delivery
- Molecular Formula: C4H7NO2
- Molecular Weight: 101.105
- Appearance/Colour: Crystalline
- Vapor Pressure: 0.0256mmHg at 25°C
- Melting Point: 229-231 °C(lit.)
- Refractive Index: 1.568
- Boiling Point: 228.9 °C at 760 mmHg
- PKA: 2.29±0.20(Predicted)
- Flash Point: 92.2 °C
- PSA： 63.32000
- Density: 1.414 g/cm3
- LogP: 0.26260
1-Aminocyclopropanecarboxylic acid(Cas 22059-21-8) Usage
|
Synthesis Reference(s) |
Synthetic Communications, 18, p. 141, 1988 DOI: 10.1080/00397918808077338Synthesis, p. 127, 1984 |
|
Biochem/physiol Actions |
1-Aminocyclopropanecarboxylic acid (ACC) exhibits anticonvulsant, anxiolytic, anti-addictive, neuroprotective and antidepressant-like effects in rats and mice. ACC does not affect memory or learning processes. |
|
Definition |
ChEBI: A non-proteinogenic alpha-amino acid consisting of cyclopropane having amino and carboxy substituents both at the 1-position. |
|
General Description |
1-Aminocyclopropanecarboxylic acid is a member of 1-aminocycloalkanecarboxylic acids. |
InChI:InChI=1/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)
22059-21-8 Relevant articles
Thermally induced and transition metal catalyzed aza-Claisen rearrangement of 2-cyclopropylideneethyl imidates: A new entry to 1-aminocyclopropanecarboxylic acids
Estieu, Karine
, p. 2975 - 2977 (1995)
(2-Cyclopropylideneethyl) acetimidates u...
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Kollonitsch,J. et al.
, p. 771 - 777 (1979)
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PRODUCTION METHOD FOR 1-AMINO CYCLOPROPANE CARBOXYLIC ACID NONHYDRATE
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Paragraph 0050-0052, (2021/05/14)
1-Aminocyclopropanecarboxylic acid non-h...
PRODUCTION METHOD FOR 1-AMINO CYCLOPROPANE CARBOXYLIC ACID NONHYDRATE
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Paragraph 0042, (2020/04/10)
1-Aminocyclopropanecarboxylic acid non-h...
Preparation method of 1-amino-cyclopropanecarboxylic acid
-
Paragraph 0012; 0014; 0016; 0018, (2018/03/26)
The invention discloses a preparation me...
A α-cycloalanine on the preparation method
-
Paragraph 0015; 0026-0028, (2017/04/29)
The invention relates to a method for sy...
22059-21-8 Process route
-
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6914-74-5
1-aminocarbonylcyclopropanecarboxylic acid
-
-
22059-21-8
aminocyclopropane-1-carboxylic acid
| Conditions | Yield |
|---|---|
|
1-aminocarbonylcyclopropanecarboxylic acid;
With
bromine; sodium hydroxide;
In
water;
at 40 ℃;
for 18h;
With
hydrogenchloride;
In
water;
at 0 ℃;
pH=5.4;
|
47%
|
|
With
bromine; sodium hydroxide;
In
water;
at 0 - 40 ℃;
for 18h;
|
47%
|
|
1-aminocarbonylcyclopropanecarboxylic acid;
With
sodium hydroxide; water; bromine;
at 0 - 40 ℃;
for 4.5 - 18h;
With
hydrogenchloride;
In
water;
at 0 ℃;
pH=5.4 - 5.7;
|
20%
|
|
With
sodium hydroxide; water; bromine;
at 0 - 40 ℃;
|
20%
|
|
With
sodium hydroxide; bromine;
In
water;
0 deg C, 6 min, 70 deg C;
|
|
|
1-aminocarbonylcyclopropanecarboxylic acid;
With
sodium hydroxide; water; bromine;
at 0 - 40 ℃;
for 21.5h;
With
hydrogenchloride;
In
water;
at 0 ℃;
pH=1.0;
|
-
-
68781-13-5
α-amino-cyclopropanecarboxylic acid hydrochloride
-
-
22059-21-8
aminocyclopropane-1-carboxylic acid
| Conditions | Yield |
|---|---|
|
With
triethylamine;
In
2-methyl-propan-1-ol; water;
pH=6;
pH-value;
Solvent;
|
84.1%
|
|
With
triethylamine;
In
dichloromethane;
|
|
|
With
potassium carbonate;
In
methanol;
at 20 ℃;
for 48h;
|
|
|
With
triethylamine;
In
2-methyl-propan-1-ol; water;
at 20 ℃;
pH=6.0;
Solvent;
Reagent/catalyst;
|
22059-21-8 Upstream products
-
861339-27-7
1-ureidocyclopropane-1-carboxylic acid
-
99420-34-5
hydantoin-5-spirocyclopropane
-
5424-29-3
2-amino-3-hydroxy-2-methyl-propionic acid
-
6914-74-5
1-aminocarbonylcyclopropanecarboxylic acid
22059-21-8 Downstream products
-
38409-70-0
1-acetamidocyclopropanecarboxylic acid
-
72784-43-1
methyl 1-aminocyclopropane-1-carboxylate
-
72784-42-0
methyl 1-aminocyclopropane-1-carboxylate hydrochloride
-
72784-47-5
ethyl 1-aminocyclopropane-1-carboxylate
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